5-HTP②-주목 받는 해외의 건강기능소재(84)
5-HTP②-주목 받는 해외의 건강기능소재(84)
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  • 승인 2005.05.11 01:13
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미 티에스아이사 등 시장 주도

5-히드록시트립토판 (5-hydroxytryptophan) 은 미국 티에스아이사(몬태나주 소재) 를 필두로 최근 Bilberry Extract, Ginkgo Biloba 제품 등을 판매하는 미국의 리니아사 등이 소재 시장을 주도하고 있으며, 완제품의 경우 줄 미국 시장을 중심으로 수백여 종 이상의 각종 건강기능식품 제형이 시장에 출시되어 있다. 대표적인 제형들을 소개한다.

HCA 지표의 가르시니아 캄보지아보다 우수한 식용 억제 효과와 Vinpocetine, Valerian 그리고 세인트 존스 워트 등을 능가하는 우울증 개선 효과 등을 무기로 한 5-HTP 의 미국 지역 이외의 향방에 귀추가 주목되고 있다.

■ 5-HTP 의 최신 연구 논문 리스트

1 : Fang LH, Zhang YH, Ku BS. Related Articles, Links
Fangchinoline inhibited the antinociceptive effect of morphine in mice. Phytomedicine. 2005 Mar;12(3):183-8. PMID: 15830839 [PubMed - in process]

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4 : Correa F, Farah CS. Related Articles, Links
Using 5-hydroxytryptophan as a probe to follow protein-protein interactions and protein folding transitions. Protein Pept Lett. 2005 Apr;12(3):241-4. PMID: 15777272 [PubMed - in process]

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J Clin Endocrinol Metab. 2005 Mar 8; [Epub ahead of print] PMID: 15755858 [PubMed - as supplied by publisher]

8 : Moore MC, Kimura K, Shibata H, Honjoh T, Saito M, Everett CA, Smith MS, Cherrington AD. Related Articles, Links
Portal 5-hydroxytryptophan infusion enhances glucose disposal in conscious dogs.Am J Physiol Endocrinol Metab. 2005 Mar 8; [Epub ahead of print] PMID: 15755767 [PubMed - as supplied by publisher]

9 : Croonenberghs J, Verkerk R, Scharpe S, Deboutte D, Maes M. Related Articles, Links
Serotonergic disturbances in autistic disorder: L-5-hydroxytryptophan administration to autistic youngsters increases the blood concentrations of serotonin in patients but not in controls. Life Sci. 2005 Mar 25;76(19):2171-83. PMID: 15733932 [PubMed - indexed for MEDLINE]

10 : Wang W, Qiu B, Xu X, Zhang L, Chen G. Related Articles, Links
Separation and determination of L-tryptophan and its metabolites by capillary micellar electrokinetic chromatography with amperometric detection.Electrophoresis. 2005 Feb;26(4-5):903-10.
PMID: 15714546 [PubMed - in process]

11 : Dad S, Bisby RH, Clark IP, Parker AW. Related Articles, Links
Identification and reactivity of the triplet excited state of 5-hydroxytryptophan. J Photochem Photobiol B. 2005 Mar 1;78(3):245-51. PMID: 15708522 [PubMed - in process]

12 : Sztanke K, Fidecka S, Kedzierska E, Karczmarzyk Z, Pihlaja K, Matosiuk D. Related Articles, Links
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PMID: 15694647 [PubMed - in process]

13 : Esteban S, Nicolaus C, Garmundi A, Rial RV, Rodriguez AB, Ortega E, Ibars CB. Related Articles, Links
Effect of orally administered L-tryptophan on serotonin, melatonin, and the innate immune response in the rat. Mol Cell Biochem. 2004 Dec;267(1-2):39-46. PMID: 15663184 [PubMed - in process]

14 : Wieronska JM, Stachowicz K, Klodzinska A, Rmialowska M, Pilc A. Related Articles, Links
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16 : Dingman S, Nash L, Hogan J, Branch C. Related Articles, Links T-maze performance after developmental exposure to 19F tagged 5-HTP in chicks. Percept Mot Skills. 2004 Dec;99(3 Pt 1):793-8. PMID: 15648472 [PubMed - indexed for MEDLINE]

17 : Keithahn C, Lerchl A. Related Articles, Links
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18 : Crespi F, Croce AC, Fiorani S, Masala B, Heidbreder C, Bottiroli G. Related Articles, Links
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20: Peng SS, Tseng WY, Chien YH, Hwu WL, Liu HM. Related Articles, Links
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<김선호·티에스아이코리아 대표>

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